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Research Initiatives
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Research Initiatives

The Research and Education Committee was formed in June 2004 to fulfill the IACP Foundation’s mission to advance the art and science of pharmacy compounding by funding research and public education initiatives within the profession. An 18-member volunteer committee worked diligently the first year to establish the priorities for giving and the application process.

Since 2005, the IACP Foundation has awarded more than $275,000 for studies researching compounded preparation potency and stability and outcomes of treatment with compounded medications. 

Current Projects:

Determination of Beyond Use Dates and Skin Penetration of Transdermal Gels Containing Multiple Active Ingredients

Principal Investigators:  John Arnold, Ph.D. and Greg Gorman, Ph.D., McWhorter School of Pharmacy, Samford University

Stability and Beyond-Use-Date Studies for Six Commonly Prescribed Agents Used in the Transdermal Treatment of Chronic Pain

Principal Investigator:  Curt R. Cyr, R.Ph., Ph.D., University of New England, College of Pharmacy

Topical Ketamine in the Treatment of Complex Regional Pain Syndrome (CRPS)

Principal Investigator:  Melissa J. Durham, Pharm.D., University of Southern California, School of Pharmacy, Keck School of Medicine of USC

Extension of Beyond the Use Dates for Combination Topical Pain Medications

Principal Investigator:  Jwala Renukuntla, Ph.D., South College School of Pharmacy

Systematic Review of Pharmacy Compounding of Pain Medication

Principal Investigator:  Mohammad S. Shawaqfeh, M.S., Pharm.D., NOVA Southeastern University, College of Pharmacy

Are Compounded Gels Efficacious?  The In Vitro and In Vivo Testing of Compounded Gels Using PAMPA, Porcine Skin and the Formalin Pain Model

Principal Investigator:  Scott Asbill, Ph.D., Professor of Pharmaceutics and Chair, Department of Pharmaceutical and Administrative Sciences, Presbyterian College School of Pharmacy

Preparation and Evaluation of a Pluronic Lecithin Organogel Containing Ricinoleic Acid for the Transdermal Delivery of Ketoprofen

Principal Investigator:  Sai HS. Boddu, Ph.D., Assistant Professor of Pharmaceutics, Frederic and Mary Wolfe Center, College of Pharmacy and Pharmaceutical Sciences, University of Toledo HSC

The Impact of Stability on the Topical Penetration of Ketoprofen Compounded in a Cream

Principal Investigator:  Adwoa Nornoo, Ph.D., Associate Professor of Pharmaceutical Sciences, Palm Beach Atlantic University

Formulation and Stability Studies of a Preservative Free Prochlorperazine Nasal Spray for Pain Relief in Migraine

Principal Investigator:  Venkata Kashyap Yellepeddi, Ph.D., Assistant Professor of Pharmaceutical Sciences, College of Pharmacy, Roseman University of Health Sciences

Beyond-Use Date (BUD) Testing Data on Erectile Dysfunction

Principal Investigator: Sarah Billings, PharmD, CDE; Director of Clinical Programs; Grove Pharmacy

Solid-State Stability of Compounded Levothyroxine Formulations

Principal Investigator: Deepa A. Rao, PhD; Assistant Professor; Jeff Fortner, RPh, PharmD; Assistant Professor; Pacific University School of Pharmacy

The Role and Value of Compounded Prescription Medications: Comparing & Contrasting Legend Pharmaceuticals vs. Compounded Pharmaceuticals in Select Disease States

Principal Investigator: William B. Lobb, RPh, PhD; University of Mississippi; Research of Pharmaceutical Sciences

Click here to view the abstract

Stability of Extemporaneously Prepared Mercaptopurine Suspensions Compounded from Tablets and Bulk Powder When Stored in Plastic and Glass Containers

Principal Investigator:  Regina F. Peacock, Ph.D., Associate Professor, Biopharmaceutical Sciences, Bernard J. Dunn School of Pharmacy, Shenandoah University

Click here to view the abstract.

Published Projects:  

CHOIiCE: The Effects of Compounded Bioidentical Transdermal Hormone Therapy on Hemostatic, Inflammatory, and Immune Factors; Cardiovascular Biomarkers; Quality of Life Measures; and Health Outcomes in Perimenopausal and Postmenopausal Women

Principal Investigator: Kenna Stephenson, MD, FAAFP; Associate Professor of Family Medicine; The University of Texas Health Sciences Center

Click here to view the abstract. *This abstract was published in the International Journal of Pharmaceutical Compounding (IJPC) January/February 2013

Click here to view the abstract. *This abstract was published in Circulation, Feb. 21; 115(8).

Click here to view the abstract.  *This abstract was published in, May 2013.  

Potency Evaluation of Morphine, Bupivicaine & Clonidine Solution for Intrathecal Administration

Principal Investigator: Richard B. Moon, PharmD, BS, RPh, FIACP

Abstract: The purpose of this study is to test potency of Morphine, Bupivicaine & Clonodine Solution for Intrathecal Administration at zero, 30, 90 and 180 days.
Click here to view project.

Potency Evaluation of Albuterol, Ipratropium Bromide and Budesonide Inhalation over 6 months

Principal Investigator: Richard B. Moon, PharmD, BS, RPh, FIACP

Abstract: The purpose of this study is to test potency of albuterol, budesonide and ipratropium bromide at zero, 15, 30, 60, 90 and 180 days and present the finding in a poster session at IACP’s Annual Meeting and Compounders on Capitol Hill. Multiple testing dates requested due to relative fragility of ADI’s involved. 

Stability of Tetracycline Hydrochloride in a Compounded Mixture

Principal Investigators: Kathleen Martin, PhD, Jade Weaver and Amanda Jacobs; University of the Incarnate Word 

Click here to view the abstract.

Potency Testing—Variability between Analytical Testing Laboratories

Principal Investigators: Matthew J. Buderer, RPh, FIACP, and Nancy Buderer, MS, CIP, Biostatistician 

Abstract: The goal of this study is to estimate the variability between analytical testing laboratories when analyzing the potency of a non-sterile compounded gel preparation. We are interested in the reliability of potency testing across laboratories, that is, the variability (differences) between laboratories. When given the same sample of an unknown potency to analyze, do the labs come up with the same result?

*This study was published in the Jan./Feb. 2009 issue of the International Journal of Pharmaceutical Compounding. 

Patient-Centered Care Services in the Community-Based Compounding Practice

Principal Investigator: Timothy B. McPherson, PhD, RPh; South Illinois University Edwardsville School of Pharmacy

Click here to view the abstract.
*This abstract was published in the American Pharmacists Association 48(2): 241, 2008.  

Clinical Trial with Transdermal Amlodipine for Treatment of Feline Hypertension

Principal Investigator: Scott R. Helms, DVM, DABVP, and Bill Mixon, RPh, MS, FIACP

Click here to view the abstract.
*An article on this study was published in the Sept./Oct. 2008 issue of the International Journal of Pharmaceutical Compounding and the Journal of the American Animal Hospital Association


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